Dideoxynucleosides

Name: Dideoxynucleosides
Brand: WUHU HUAREN SCIENCE AND TECHNOLOGY CO., LTD.

Dideoxynucleosides are modified nucleosides that lack the 3’-OH group on their sugar moiety, which is required for the formation of the phosphodiester bond that links nucleotides in a growing DNA strand. Because of this, dideoxynucleosides act as chain-terminators during DNA synthesis.

Types of Dideoxynucleosides

2′,3′-Dideoxyadenosine
CAS No. 4097-22-7

2′,3′-Dideoxycytidine
CAS No. 7481-89-2

2',3'-Dideoxyguanosine
CAS No. 85326-06-3

2',3'-Dideoxythymidine
CAS No. 3416-05-5

2',3'-Dideoxyuridine
CAS No. 5983-09-5

2',3'-Dideoxyinosine
CAS No. 69655-05-6

The Application of HUAREN's Dideoxynucleosides

DNA Sequencing: HUAREN's Dideoxynucleosides are essential for Sanger sequencing, enabling precise DNA sequence determination by terminating DNA synthesis.

PCR: The Dideoxynucleosides are used in chain termination PCR for mutation detection and genotyping.

Antiviral Research: Inhibits viral DNA polymerases, aiding in the development of antiviral drugs.

Cancer Research: The Dideoxynucleosides block DNA synthesis in cancer cells, useful for therapeutic studies.

Site-Directed Mutagenesis: Facilitates specific DNA sequence changes to study gene function.

Enzyme Kinetics: The Dideoxynucleosides are used in assays to study DNA polymerase activity.

Synthetic Biology: Helps in creating artificial genes and genetic circuits.

Why Choose Dideoxynucleosides from HUAREN?

Long-Term Stability

Stability Testing: Dideoxynucleosides undergo stability testing to ensure they remain stable and retain their quality over time.

Shelf Life: Clear storage guidelines and shelf life information are provided to maintain product stability.

High Purity and Quality

Rigorous Quality Control: HUAREN ensures their dideoxynucleosides meet high purity standards, typically exceeding 98%, through stringent quality control processes.

Consistency: Each batch is tested for consistency, ensuring reliable and reproducible results in your experiments.

Advanced Manufacturing

State-of-the-Art Facilities: HUAREN utilizes advanced manufacturing facilities and technologies to produce high-quality dideoxynucleosides.

Controlled Environment: Production is carried out in a controlled environment to prevent contamination and maintain product integrity.

Comprehensive Testing

Purity Analysis: Techniques such as High-Performance Liquid Chromatography (HPLC) are used to verify the purity of the dideoxynucleosides.

Contaminant Screening: Products are screened for potential contaminants, including heavy metals and microbial contamination.

Wide Range of Applications

Versatility: Suitable for DNA sequencing, PCR, antiviral research, cancer research, site-directed mutagenesis, enzyme kinetics, and synthetic biology.

Technical Support

Expert Assistance: HUAREN provides excellent customer and technical support to help researchers integrate dideoxynucleosides into their workflows.

Documentation: Detailed batch records and certificates of analysis (CoA) are provided, documenting the quality control tests and results.

Regulatory Compliance

Industry Standards: Manufacturing processes comply with industry standards and regulations, ensuring quality and safety.

Certifications: Relevant certifications, such as ISO, further attest to their commitment to quality.

Customer Satisfaction

Positive Feedback: A track record of positive feedback from customers reflects satisfaction with product quality and performance.

Continuous Improvement: Customer feedback is used to continuously improve the product and manufacturing processes.

Cost-Effective: Offers high-quality dideoxynucleosides at competitive prices, providing value for money without compromising on quality.

Reach Out To Huaren Science!

If you have questions about our Amidites, Nucleotides or Nucleosides, feel free to contact Huaren Science's specialists for timely support!